Tens of millions of people struggle with depression every day. The Hope for Depression research Foundation (HDRF) is working to change the way depression is diagnosed, treated, viewed and researched.

You can help with your voice, your dollars, and your compassion.

Learn how here.

Help us fund the most advanced depression research today

Depression affects over
20 million people in the U.S.
each year,
regardless of age,
or socio-economic level.

The Staggering Statistics about Depression

Did you know that it...

  • Is the leading cause of disability in the U.S. for ages 15-44?
  • Is the primary reason why a person dies of suicide every 15 minutes?
  • Will be the leading global health burden by the next decade?
more depression facts

The Crisis in Depression Treatment and Research

Since the advent of the latest group of
anti-depressants (SSRIs and SNRIs) almost thirty
years ago, there has been virtually no change
in the treatment of depression or new category
of medication.

Yet over 50% of patients with major depression
do not respond to existing treatments.

more info

HDRF's Mission

Our goal is to fund the most advanced neuroscience research to:

  • find the root causes
  • develop a medical diagnosis
  • discover new treatments
  • and find methods to prevent depression.
Depressive Disorders

HDRF's work encompasses depression and its related mood disorders:

  • bipolar disorder
  • postpartum depression
  • post-traumatic stress disorder
  • anxiety disorder
more about our mission

Our Unique, Collaborative Research Strategy
HDRF is the leading non-profit focused solely on depression research,
with an unprecedented Depression Research Road Map created and
executed by our team of world renowned neuroscientists.

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Young Neurons in the Hippocampus
Latest Research

The Depression Task Force has made remarkable research progress in 2014, which is outlined in our Research Report.

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Special Events

An important focus of HDRF's mission is to educate the public, correct misinformation, and reduce the stigma that still surrounds illnesses of the mind/brain.

"Messengers of Hope"

Outstanding celebrity speakers who have shared their own experience with depression or a related mood disorder have appeared at our Annual Seminars.

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