Support Us
Every act of support
moves science forward.
Whether you name a research grant, shop with purpose, or give your time — your contribution directly accelerates breakthrough depression research.
DONOR CIRCLE
Fund The Breakthrough
More than 350 million people struggle with depression across the globe. Despite its scale, depression is under-funded, under-researched and still widely misunderstood.
Millions are waiting for discoveries that can change their lives. We’re closer than ever to the next generation of treatments, but we need your support.
By partnering with
HDRF, you fund the science necessary to transform the way depression is diagnosed,
treated and prevented. Join us on the last frontier of medicine — the mind and brain.
100% of Your Gift Funds Research
A private foundation underwrites all administrative expenses. Every dollar you give goes directly to depression research.
WHAT YOUR GIFT MAKES POSSIBLE
$500
Supports one day of laboratory analysis.
$3,125
Funds genetic testing for one research participant.
$8,000
Per year allows for compensation and recruitment costs for one participant.
$12,500
Per year cover highly advance brain
imaging for one research participant.
$575
Enables a week of postdoctoral research.
$300K
Funds one year of new pilot clinical trial.
Why It Matters
“Private philanthropy allows us to explore bold ideas that would otherwise remain unexplored. HDRF’s support helps move the field forward in ways that benefit patients sooner.”
– HDRF-funded researcher
Become a Research Partner
Monthly donors provide steady funding that allows scientists to plan ambitious, multi-year studies. Join our Hope365 community and help sustain the research that drives discovery forward.
Ready to make history?
Reach out to our Director of Development to explore Donor Circle membership and name a research grant that carries your legacy.
Mary Kay Wright
Director of Development, HDRF
Your Gift at Work
20 Gene Targets
Out of the human body's 20,000 genes, our scientists have pinpointed 20 gene targets that can potentially lead to novel treatments, each validated in both animal models and human brain tissue.
Potential Blood Test for Depression
HDRF-funded research has discovered biomarkers that could transform diagnosis from subjective to objective
Clinical Results
Early human trials are showing remarkable results. 80% remission rates in treatment-resistant depression.
SHOP FOR HOPE
Shop with Purpose.
Give with Hope.
HDRF is proud to partner with a curated selection of lifestyle brands. A percentage of all sales from these collections is donated directly to depression research — so every purchase you make moves science forward.
hamilton jewelers
Charms of Hope Collection
Elegant charm jewelry designed to carry meaning. A portion of each piece sold from the Charms of Hope Collection benefits HDRF research into treatment-resistant depression.
HDRF x Jeffrey Levinson
Soluna Bag
A beautifully crafted collaboration bag - part art object, part statement of hope. Proceeds from this exclusive HDRF partnership directly fund neuroscience research.
HDRF x fishers finery
Silk Pillowcase
Luxuriously soft 100% silk pillowcase co-created with HDRF. A beautiful everyday reminder that caring for your wellbeing and funding hope can go hand in hand.
Volunteer
Give your time.
Change the future.
If you're passionate about advancing depression research and raising awareness, we'd love your help. Volunteers are a vital part of how HDRF spreads its mission across events, communities, and campaigns.
Ways to volunteer
Event Support
Help coordinate our Race of Hope events — from check-in and logistics to cheering on runners and managing sponsor booths.
Awareness & Outreach
Share HDRF's mission in your community — at workplaces, schools, or social channels — to reduce stigma and raise awareness of depression as a medical illness.
Creative & Digital Skills
Contribute your design, photography, writing, or social media skills to help HDRF tell its story more powerfully.
Fundraising
Create your own fundraising campaign on behalf of HDRF or help organize peer-to-peer giving drives in your network.
The Hope for Depression Research Foundation is recognized by the Internal Revenue Service as a not-for-profit public charity (Tax ID 20-4559210), contributions to which are deductible for income and gift tax purposes. All contributions are tax-deductible to the full extent allowed by law.