Tens of millions of people struggle with depression every day. The Hope for Depression research Foundation (HDRF) is working to change the way depression is diagnosed, treated, viewed and researched.
You can help with your voice, your dollars, and your compassion.
Help us end depression through research today
Depression affects over
18 million people in the U.S.
each year,
regardless of age,
gender,
race,
religion,
or socio-economic level.
Upcoming Events
The Nineteenth Annual HOPE Luncheon Seminar
Wednesday, November 12, 2025
NYC, New York
11:30 a.m.
The Staggering Statistics about Depression
Did you know that depression...
- Is the Number One cause of disability worldwide?
- Is the primary reason why a person dies of suicide every 14 minutes?
- Takes an annual toll on U.S. business of $100 billion per year?
The Crisis in Depression Treatment and Research
been little progress in the treatment of depression. All common
depression medications today are based on the same formula.
But over 50% of patients with major depression
do not respond to the existing treatments.
HDRF's Mission
Our goal is to fund the most advanced neuroscience research to:
- identify the root causes of depression
- develop more sophisticated medical diagnoses
- discover new treatments
- find new methods to prevent depression
Depressive Disorders
HDRF's research encompasses depression and its related mood disorders:
- bipolar disorder
- postpartum depression
- post-traumatic stress disorder
- anxiety disorder
Young Neurons in the Hippocampus
Latest Research Report
The Depression Task Force has made remarkable research progress, which is outlined in our Research Report.
read moreSpecial Events
An important focus of HDRF's mission is to educate the public, correct misinformation, and reduce the stigma that still surrounds illnesses of the mind/brain.
"Messengers of Hope"
Outstanding celebrity speakers who have shared their own experience with depression or a related mood disorder have appeared at our Annual Seminars.
