2009 HDRF funded Research Publications

• Central infusion of Interleukin-1 receptor antagonist blocked the reduction in social investigation produced by prior stressor exposure.  Physiology & Behavior, 98, 139-146. 2009. (Arakawa, H., Blandino, Jr., P. & Deak, T.)
• To lose the frame of action: A selective deficit in avoiding unpleasant objects following unilateral temporal lobe lesion. Neurocase, 15: 261-270. 2009. (Bamford, S., Turnbull, O.H., Coetzer, R. & Ward, R.)
• Attentional modulation of emotional stimulus processing in patients with major depression—Alterations in prefrontal cortical regions. Neuroscience Letters Oct 2;463(2):108-13. 2009. (Bermpohl, F., Walter, M., Sajonz, B., Lücke, C., Hägele, C., Sterzer, P., Adli, M., Heinz, A., Northoff, G.)
• Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress. Brain, Behavior & Immunity, 23, 958-968. 2009. (Blandino Jr., P, Barnum, C.J., Solomon, L.G., Larish, Y., Lankow, B.S. & Deak, T.)
• Thyroid disorders in mental patients. Current Opinion in Psychiatry. 22, no. 4, p.391-395. 2009. (Bunevicius, R.)
• Thyroid disease and mental disorders: cause and effect or only co-morbidity? Current Opinion in Psychiatry. 23: 363-368. 2009. (Bunevicius, R. & Prange, A.J.)
• The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats. Developmental Psychobiology, 51(1): 34-46. 2009. (Burgdorf, J, Panksepp, J, Brudzynski, S. M, Beinfeld, M. C, Cromwell, H. C, Kroes, R. A, & Moskal, J. R)
• Stress-induced, glucocorticoid-dependent strengthening of glutamatergic synaptic transmission in midbrain dopamine neurons. Neuroscience Letters, 452 (3): 273-6. 2009. (Daftary S.S., Panksepp J., Dong Y. & Saal, D.B.)
• Validation of a novel social investigation task that may dissociate social motivation from exploratory activity. Behavioural Brain Research, 199, 326-333. 2009. (Deak, T., Arakawa, H., Bekkedal, M.Y.V. & Panksepp, J.)
• Is Our Self Nothing but Reward? Neuronal Overlap and Distinction between Reward and Personal Relevance and Its Relation to Human Personality PLoS ONE, Volume 4, Issue 12. 2009. (Enzi, B., de Greck, M.,  Prösch, U., Tempelmann, C. & Northoff, G.)
• Neural mechanisms of grief regulation.  Biological Psychiatry, vol. 66 (1), 33-40. 2009.  (Freed, P.J., Yanagihara, T.K., Hirsch, J., & Mann, J. J.)
• Altered Negative BOLD Responses in the Default-Mode Network during Emotion Processing in Depressed Subjects Neuropsychopharmacology; 34(4):932-843. 2009. (Grimm, S., Boesiger, P.,  Beck, J., Schuepbach, D., Bermpohl, F., Walter, M., Ernst, J., Hell, D., Boeker, H. & Northoff, G.)
• Increased Self-Focus in Major Depressive Disorder Is Related to Neural Abnormalities in Subcortical-Cortical Midline Structures. Human Brain Mapping; 30(8):2617-27. 2009. (Grimm, S., Ernst, J., Boesiger, P., Schuepbach, D., Hell, D., Boeker, H. & Northoff, G.)
• Understanding the self: a cultural neuroscience approach. Progress in Brain Research, Vol. 178, ISSN 0079-6123. 2009. (Han, S., & Northoff, G.)
• The effects of prenatal stress on social motivation in rat pup. Stress; 12(3):250‐8. 2009. (Harmon, K.M., McFarland, A.M., Beckwith, T.J., Greenwald, M. & Cromwell , H.C)
• In vivo Cocaine Experience Generates Silent Synapses.  Neuron, 63:40-47. 2009. (Huang, Y.H., Lin ,Y., Mu, P., Lee, B.R., Brown, T.E., Wayman, G.A., Marie, H., Liu, W., Yan, Z., Sorg, B.A., Schlüter, O.M., Zukin, R.S. & Dong, Y.)
• Enriched Environment Experience Overcomes Learning Deficits and Depressive-Like Behavior induced by Juvenile Stress. PLoS One. 4(1). 2009. (Ilin, Y., Richter-Levin, G.)
• ERK2 and CREB activation in the amygdala when an event is remembered as “Fearful” and not when it is remembered as “Instructive”. J Neurosci Res. Jun;87(8):1823-31. 2009. (Ilin Y, Richter-Levin G.)
• Homeostatic Synapse-driven Membrane Plasticity in Nucleus Accumbens Neurons.  Journal of Neuroscience, 29 (18): 5820-31. 2009. (Ishikawa, M., Moyer, J., Wolf, J.A., Quock, R.M., Davis, N.M., Hu, X.T., Schlüter, O.M. & Dong, Y.)
• Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking. Proceedings of the National Academy of Sciences of the USA, 106: 19168-19173. 2009. (Land, B. B., Bruchas, M. R., Schattauer, S., Giardino, W. J., Aita, M., Messinger, D., Hnasko, T. S., Palmiter, R. D., & Chavkin, C.)
• Two different putative genetic animal models of childhood depression – A review. Progress in Neurobiology, 88, 153–169. 2009. (Malkesman, O. & Weller, A.)
• Effect of chronic stress on behavior and cerebral oxidative metabolism in rats with high or low positive affect. Neuroscience, 164: 963-974. 2009. (Mällo, T., Matrov, D., Kõiv, K. & Harro, J)
• Wistar‐Kyoto rats as an animal model of anxiety vulnerability: Support for a hyper‐vigilance hypothesis. Behav Brain Res. 204(1):162‐8. 2009. (McAuley, J.D., Stewart, A.L., Webber, E.S., Cromwell, H.C., Servatius, R.J. & Pang, K.C.H.)
• Repeated Cocaine Exposure Induces Sensitization of Ultrasonic Vocalization in Rats. Neuroscience Letter, 453 (1): 31-5. 2009. (Mu, P., Fuchs, T., Saal, D.B., Sorg, B., Dong, Y. & Panksepp, J.).
• The trans-species core SELF: The emergence of active cultural and neuro-ecological agents through self-related processing within subcortical-cortical midline networks Consciousness and Cognition 2009 Mar;18(1):193-215. 2009. (Panksepp, J., & Northoff, G.)
• From high anxiety trait to depression: a neurocognitive hypothesis. Trends Neurosci. 32(6):312-20. 2009. (Sandi, C. & Richter-Levin, G.)
• The Relationship Between Aberrant Neuronal Activation in the Pregenual Anterior Cingulate, Altered Glutamatergic Metabolism, and Anhedonia in Major Depression. Archives of General Psychiatry, 66(5): 478-486. 2009. (Walter, M., Henning, A., Grimm, S., Schulte R.F., Beck, J., Dydak, U., Schnepf, B., Boeker, H., Boesiger, P. & Northoff, G.)