2014 HDRF funded Research Publications

Maternal care differentially affects synaptic plasticity in the dorsal and ventral hippocampus. (In press) Neuropsychopharmacology. (Nguyen H.B., Bagot R.C., Diorio J., Wong T.P., Meaney M.J.)

BDNF Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes. (In press) Development and Psychopathology. (Li C., Pan H., Tuan T.A., Teh A.L., Mah S.M., Li Y., Cehn H., Broekman B.F.P., Buschdorf J.P., Chong Y.S., Kwek K., Saw S.M., Gluckman P.D., Fortier M.V., Rifkin-Graboi A., Kobor M.S., Qiu A., Meaney M.J., Holbrook J.D.)

Brain-derived neurotrophic factor (BDNF) in the nucleus accumbens mediates individual differences in behavioral responses to a natural, social reward. (Under review) Nature Neuroscience. (Shahrokh D., Ian C., Hellstrom I.C., Josie C., Diorio J., Christian Caldji C., Meaney M.J.)

Defining Critical White Matter Pathways Mediating Successful Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Biological Psychiatry. 2014. (Riva-Posse, P., Choi, K.S., Holtzheimer, P.E., McIntyre, C.C., Gross, R.E., Chaturvedi, A., Crowell, A.L., Garlow, S.J., Rajendra, J.K., Mayberg, H.S.)

Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. Molecular Psychiatry. 2014. (Nasca C., Bigio B., Zelli D., Nicoletti F., and McEwen B.S.)

Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat Neurosci 2014. (Likhtik, E., Stujenske J.M., Topiwala M., Harris A.Z., and Gordon J.A.)

Epigenetic signaling in psychiatric disorders. Molecular Biology, in press. 2014. (Pena C.J., Bagot R.C., Labonté B., Nestler E.J.)

Epigenetic mechanisms in depression. Dialogues Clinical Neuroscience, in press. 2014. (Bagot R.C., Labonté B., Pena C.J., Nestler E.J.)

Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. Neuropsychopharmacology, in press. 2014. (Sarkar A., Chachra P., Kennedy P., Pena C.J., Desouza L.A., Nestler E.J., Vaidya V.A.)

Dendritic inhibition in the hippocampus supports fear learning. Science. 2014. (Lovett-Barron M., Kaifosh P., Kheirbek M.A., Danielson N., Zaremba J.D., Reardon T.R.,  Turi G.F., Hen R., Zemelman B.V., Losonczy A.)

Functional dissociation of adult-born neurons along the dorsoventral axis of the dentate gyrus. Hippocampus. 2014. (Wu M.V., Hen R.)

From Psychiatric Disorders to Animal Models: A Bidirectional and Dimensional Approach. Biological Psychiatry. 2014. (Donaldson Z.R., Hen R.)

Impact of Social Status and Antidepressant Treatment on Neurogenesis in the Baboon Hippocampus. Neuropsychopharmacology. 2014. (Wu M.V., Shamy J.L., Bedi G., Choi C.W., Wall M.M., Arango V., Boldrini M., Foltin R.W., Hen R.)

Global state measures of the dentate gyrus gene expression system predict antidepressant-sesitive behaviors. PLoS One. 2014. (Samuels B.A., Leonardo E.D., Dranovsky A., Williams A., Wong E., Nesbitt A.M., McCurdy R.D., Hen R., Alter M.)Lesions of the paraventricular nucleus of the thalamus differentially affect sign- and goal-tracking conditioned responses. Eur J Neuroscience. October 2015. (Haight J.L., Fraser K.M., Akil H., Flagel S.B.)